主题：Dynamical Data Science and AI in Medicine

报告人：Luonan CHEN, Professor, Key Laboratory of Systems Biology, Chinese Academy of Sciences

主持人：Tianwei YU, Professor & Associate Dean (Student Affairs), School of Data Science, CUHK-Shenzhen

日期：6 March (Wednesday), 2024

时间：11:00 AM - 12:00 PM, Beijing Time

形式：Hybrid

地点：103 Meeting Room, Daoyuan Building

SDS视频号直播：

语言：English

摘要：

In this talk, Prof. Luonan Chen will present a new concept "dynamical data science" in AI applications of biology and medicine for studying dynamical processes and disease progressions, including dynamic network biomarkers (DNB) for early-warning signals of critical transitions, spatial-temporal information (STI) transformation for short-term time-series prediction, and partial cross-mapping (PCM) for causal inference among variables. These methods are all data-driven or model-free approaches but based on the theoretical frameworks of nonlinear dynamics. We show the principles and advantages of dynamics-based data-driven approaches as explicable, quantifiable, and generalizable. In particular, dynamics-based data science approaches exploit the essential features of dynamical systems in terms of data, e.g. strong fluctuations near a bifurcation point, low-dimensionality of a center manifold or an attractor, and phase-space reconstruction from a single variable by delay embedding theorem, and thus are able to provide different or additional information to the traditional approaches, i.e. statistics-based data science approaches. The dynamical-based data science approaches will further play an important role in the systematical research of various fields in biology and medicine as well as AI.

简介：

Luonan Chen received BS degree in the Electrical Engineering, from Huazhong University of Science and Technology, and the M.E. and Ph.D. degrees in the electrical engineering, from Tohoku University, Sendai, Japan, in 1988 and 1991, respectively. From 1997, he was an associate professor of the Osaka Sangyo University, Osaka, Japan, and then a full Professor. Since 2010, he has been a professor and executive director at Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences. He was elected as the founding president of Computational Systems Biology Society of OR China, and Chair of Technical Committee of Systems Biology at IEEE SMC Society. In recent years, he published over 400 journal papers and three monographs (books) in the area of bioinformatics, nonlinear dynamics and machine learning.